PacBio SMRT technology is capable of generating extremely long DNA sequencing reads (on average 8,500bp) with no systematic error, no sequence context bias, and no requirement for amplification. These unique properties allow PacBio to access regions of the genome - and areas of biology - previously unattainable. In this seminar, Dr Singh will give a scientific account of his hands-on experience with PacBio data from projects completed in the Asia Pacific region. The focus will be on bioinformatics tools and new approaches for dealing with long-read sequencing data. Key applications include de Novo Assembly / Genomes Finishing, Full-length Transcript Sequencing (IsoSeq), Repeat Expansions and Structural Variation, Haplotype Phasing, Epigenome Analysis & Base Modification Detection.  Dr Siddarth Singh is a senior scientist at PacBio responsible for overseeing informatics and application development across the Asia Pacific region. Dr Singh has many years of experience in Next Generation Sequencing analysis across multiple applications and platforms. Dr Singh has a PhD in Bioinformatics from Devi Ahilya University, India.